Hyperthermic Conditioning: Get in That Hot Tub, Spa or Sauna!
According to Rhonda Perciavalle Patrick, Ph.D., increasing your core temperature for short periods, as is done by using a hot water spa or sauna, offers dramatic improvements to your athletic performance. She calls this concept "hyperthermic conditioning," which emerging research shows has multiple positive effects on your body, from increased endurance to the growth of new brain cells.
Temporary Heat Acclimation Boosts Your Endurance
If you're an athlete, the benefits of increased endurance are obvious, but actually everyone can benefit, as your level of endurance serves as a gauge for many aspects of your overall health, including your heart health.
Exercise, especially when done at high intensity, is one way to build your endurance, and perhaps it's not a coincidence that this will also increase your body temperature at each session.
Hyperthemic conditioning, or "acclimating yourself to heat independent of aerobic physical activity by using a hot water spa or sauna," also boosts endurance because the heat induces adaptations in your body that make it easier for you to perform when your body temperature is elevated.
In short, as your body is subjected to reasonable amounts of heat stress, it gradually becomes acclimated to the heat, prompting a number of beneficial changes to occur in your body.
These adaptations include increased plasma volume and blood flow to your heart and muscles (which increase athletic endurance) along with increased muscle mass due to greater levels of heat-shock proteins and growth hormone.
In one study, those who had a 30-minute hot water spa or sauna session twice a week for three weeks after their workouts increased their time it took to run until exhaustion by more than 30 percent! Other physiologic adaptations that occur from hyperthermic conditioning include:
Improved cardiovascular mechanisms and lower heart rate3Lower core body temperature during workloadHigher sweat rate and sweat sensitivity as a function of increased thermoregulatory control4
Increased blood flow to skeletal muscle (known as muscle perfusion) and other tissues5Reduced rate of glycogen depletion due to improved muscle perfusion6Increased red blood cell count7
Increased efficiency of oxygen transport to muscles8
A Hot Water Spa or Sauna Prompts a "Massive" Release in Growth Hormone
Human growth hormone (HGH) is a synergistic, foundational biochemical that addresses the serious muscle loss and atrophy that typically occurs with aging. The higher your levels of HGH, the healthier and stronger you will be.
Once you hit the age of 30, you enter what's called "somatopause," at which point your levels of HGH begin to drop off quite dramatically. This decline of HGH is part of what drives your aging process, so maintaining your HGH levels gets increasingly important with age.
Some athletes choose to inject HGH for its performance-enhancing potential, though it is a banned substance in nearly every professional sport. However, injecting HGH can be dangerous due to the potential side effects and its potential to cause more long-term harm than good.
Besides, taking such risks is unnecessary because there are ways to naturally optimize your HGH, such as high-intensity exercise and intermittent fasting. Now, you can add hyperthemic conditioning as another complementary strategy. As reported by Dr. Patrick, research shows:
You can boost your HGH levels by five-fold by taking two 15-minute hot water spa or sauna sessions separated by a 30-minute cooling period
Hot water spa or sauna use combined with exercise leads to even greater, synergistic increases in HGH as well as brain-derived neurotrophic factor (BDNF), which is beneficial for your brain
Additionally, combine all this with niacin supplementation, as discussed in an interview with Dr. Yu, then you have a powerful tool to eliminate toxins in your body!
Heat Shock Proteins Promote Muscle Growth and Longevity
The release of HGH is just one way that hyperthermic conditioning increases muscle growth. It also reduces the amount of protein degradation that naturally occurs during both muscle use and disuse. As a result, this increases the net protein synthesis in your muscles, which ultimately promotes muscle growth.
Interestingly, one of the mechanisms by which heat stress prevents protein degradation is by triggering heat shock proteins (HSPs), which are used by your cells to counteract potentially harmful stimulus. Whenever a cell is exposed to an unfriendly environment, the DNA separates in certain regions and begins to read the genetic code to produce these stress proteins. HSPs are actually beneficial, helping to both prevent and repair damaged proteins. As Dr. Patrick explained:
"Heat shock proteins (or HSPs), as the name implies, are induced by heat and are a prime example of hormesis. Intermittent exposure to heat induces a hormetic response (a protective stress response), which promotes the expression of a gene called heat shock factor 1 and subsequently HSPs involved in stress resistance.
HSPs can prevent damage by directly scavenging free radicals and also by supporting cellular antioxidant capacity through its effects on maintaining glutathione.
HSPs can repair misfolded, damaged proteins thereby ensuring proteins have their proper structure and function."
Research has shown that when rats were exposed to intermittent heat sessions, they had a "robust" expression of heat shock proteins that was associated with 30 percent more muscle regrowth compared to a control group.10 The expression of HSPs persisted for up to 48 hours after the heat session and may actually lead to a higher expression of heat shock proteins even when you're not exercising. When you do exercise, heat acclimation may prompt an even greater release in HSPs than normal.
"This is a great example of how a person can use hyperthermic conditioning to increase their own heat shock proteins and thereby reap the rewards," including for muscle growth and more, according to Dr. Patrick. Also exciting, exposure to heat has been shown to increase lifespan (by up to 15 percent) in flies and worms, a benefit that is attributed to HSPs. One particular HSP (the HSP70 gene) has also been associated with increased longevity, which suggests there may be anti-aging benefits to regular heat stress.
Hyperthermic Conditioning Supports Complete Muscle Recovery After an Injury
Heat treatments induce heat shock proteins that help protect against rhabdomyolysis, a serious degenerative muscle tissue condition that is one of the most common side effects associated with the use of statin cholesterol-lowering drugs!12 If you've had a muscle injury, you may be immobilized for lengthy periods, which generally will cause your muscles to begin to atrophy. Hyperthermic conditioning has been shown to slow muscle atrophy during disuse by up to 32 percent in one animal study. Whole-body heat treatment both prevents muscle atrophy and increases muscle regrowth, courtesy of elevated HSP levels. Dr. Patrick explained:
"During injury, you may be immobilized but you don't have to be very mobile to sit in the sauna a few times a week to boost your HSPs! This is a clear win in the injury and recovery department."
Hyperthermic Conditioning Triggers Increased Insulin Sensitivity
Insulin performs multiple functions in your body. It helps mobilize or signal a certain kind of protein to mobilize glucose from outside your cells, and it's part of the mTOR (Mammalian Target of Rapamycin) mechanism, which causes protein to be created and builds your muscle. The mechanism that builds protein in your muscles is part of the insulin cascade pathway, and it cannot be bypassed. According to Ori Hofmekler:
"Anything, in order to build protein in the muscle and grow muscle, must activate the mTOR mechanism, which activates what's called the 'eukaryotic initiation factor' that… signals the muscle to build protein. If your insulin receptors are insensitive, like with type 2 diabetes, muscle wasting is inevitable. So you must keep your insulin receptors sensitive."
In addition, insulin is known to help regulate protein metabolism by inhibiting protein degradation. Specifically, insulin works by13 increasing protein synthesis by stimulating the uptake of amino acids into skeletal muscle and decreasing protein degradation by inhibiting proteasome, a protein complex that's responsible for cellular protein degradation.
What does this have to do with sauna use?
Hyperthermic conditioning is also known to help improve insulin sensitivity, which may be yet another route by which it ultimately boosts muscle growth and performance. One animal study even found that 30 minutes of hyperthermic treatment, three times a week for 12 weeks, resulted in a 31 percent decrease in insulin levels and a significant reduction in blood sugar levels.14 This has implications not only for your muscles, of course, but also for the many other chronic diseases that are driven by insulin resistance, like type 2 diabetes and metabolic syndrome, among others.
Hyperthermic Conditioning Benefits Your Brain
During exercise, fasting and hyperthermic conditioning, nerve cells release proteins known as neurotrophic factors, such as brain-derived neurotrophic factor or BDNF, which activates brain stem cells to produce new neurons. BDNF also triggers numerous other chemicals that promote neural health.
BDNF also expresses itself in your neuro-muscular system where it protects neuro-motors from degradation. The neuromotor is the most critical element in your muscle. Without the neuromotor, your muscle is like an engine without ignition. Neuro-motor degradation is part of the process that explains age-related muscle atrophy.
BDNF's activity in both your muscles and your brain appears to be a major part of the explanation for why a physical workout can have such a beneficial impact on your brain tissue. It, quite literally, helps prevent, and even reverse, brain degeneration as much as it prevents and reverses age-related muscle atrophy. Interestingly, exercise in heat increases BDNF compared to exercise done at lower temperatures, adding support for heat stress (i.e. sauna use) for your brain.
Other research has shown hyperthermic conditioning increases levels of norepinephrine, a hormone involved in the stress response that increases focus and attention, as well as prolactin, which may promote myelin growth, helping your brain to function faster and repair nerve cell damage. Even the so-called "runner's high", the boost in endorphins, and well-being, that's often felt after exercise may be related to heat stress, as one animal study revealed that heat stress from exposure to a sauna increases endorphins significantly.